University of California, Irvine

Andy Thai, Ph.D.

Computer Science, Donald Bren School of ICS  ·  Anatomy & Neurobiology, School of Medicine

Researcher in geometric processing, computer vision, and deformable image registration for biomedical and neuroscience imaging.

Portrait of Andy Thai
Irvine, California

About

I am an academic researcher developing geometric and numerical algorithms for biomedical and neural visual data — from mouse-brain registration to dynamic cardiac reconstruction.

I work with Prof. Gopi Meenakshisundaram and Prof. Xiangmin Xu in the Xu Lab on the synchronization, registration, and visualization of multimodal mouse brain models.

Research Interests

Image Registration Medical & Neural Imaging Optimization Image Processing Geometric Processing Visualization Animation

Selected Publications

Also Published

Projects & Software

CNCM AAV Enhancer Gallery

Gallery of AAV enhancer sequences for targeted gene delivery.

RegBoost

A 3D Laplacian interpolation framework using geometric feature priors for mouse brain image registration. It complements any registration pipeline.

DVFOpt

An optimization procedure that adjusts any DVF to eliminate local folding artifacts with minimal deviation from the input field.

Implicit Heart

An implicit function representation for dynamic cardiac data, enabling 3D and 4D reconstruction and ejection fraction estimation.

News

  • Sep 2025

    My dissertation, Geometric and Numerical Algorithms for Biomedical and Neural Visual Data Processing, has been made available at ProQuest.

  • Aug 2025

    Completed my Ph.D. defense at UC Irvine.

  • May 2025

    Our paper on brain endothelial cell targeting has been published in Neuron.

  • Jan 2025

    Our RegBoost paper has been published in NeuroImage.

Teaching, Talks & Service

Teaching
  • ICS 6N: Linear Algebra
    Teaching Assistant, Reader, and Instructor Support. UC Irvine, multiple terms, 2019 to 2024.
  • ICS 32, 32A, 33, and 45C
    Teaching Assistant and Reader. UC Irvine, 2018 to 2021. Programming with Software Libraries, Intermediate Programming, and C++ as a Second Language.
  • COGS 189: Brain-Computer Interfaces
    Instructional Assistant. UC San Diego, 2018.
Talks
  • Automatic segmentation and implicit surface representation of dynamic cardiac data
    CGI 2024, Geneva, Switzerland.
  • RUBI-PAL Robotics
    Contextual Robotics Institute Forum, UC San Diego, 2017 to 2018.
Service
  • Session Chair
    CGI 2024.
  • Invited Panelist
    UCSD ACSP Post-Grad Panel, 2021 to 2024. Cal-Bridge Students Panel, 2022. CSP Alumni Q&A, 2021.
  • Leadership Coach
    DECADE PLUS, UC Irvine, 2019 to 2021.
  • Leadership & Outreach
    Various roles with the UCSD Chancellor's Scholars Program and Alliance, 2014 to 2018.

Contact

Correspondence

Email: [enable email]
Web: ics.uci.edu/~athai5

Office

By appointment. Falling Leaves Foundation Medical Innovation Building, or Donald Bren Hall.