Andy Thai, Ph.D.

Donald Bren School of ICS, Department of Computer Science
School of Medicine, Department of Anatomy and Neurobiology
UC Irvine

I am an academic researcher studying techniques in geometric processing, computer vision, and deformable image registration for biomedical and neuroscience applications. I work with Prof. Gopi Meenakshisundaram and collaborators in the Xu Lab for synchronization, registration, and visualization of multimodal mouse brain models.

Image Registration Medical/Neural Imaging Optimization Image Processing Geometric Processing Visualization Animation

Download CV Google Scholar GitHub

News

[Sep 2025] My dissertation, Geometric and Numerical Algorithms for Biomedical and Neural Visual Data Processing, has been made available at ProQuest.
[Aug 2025] Completed Ph.D. defense at UC Irvine.
[May 2025] Our paper on brain endothelial cell targeting has been published at Neuron.
[Jan 2025] Our RegBoost paper has been published to NeuroImage.

Publications

Specific targeting of brain endothelial cells using enhancer AAV vectors — Neuron, 2025.

E. Velazquez-Rivera, O. Dey, N. S. Kim, W. Cao, Q. Ye, P. Gao, Andy Thai, J. K. Nguyen, H. Zhang, J. T. Ting, M. Gopi, B. Ren, T. C. Holmes, X. Xu · DOI
RegBoost: Enhancing mouse brain image registration using geometric priors and Laplacian interpolation — NeuroImage, 2025.

A. N. Chilaparasetti, Andy Thai, P. Gao, X. Xu, M. Gopi · DOI
Brain image data processing using collaborative data workflows on Texera — Frontiers in Neural Circuits, 2024.

Y. Ding, Y. Huang, P. Gao, Andy Thai, A. Chilaparasetti, M. Gopi, X. Xu, C. Li · DOI
Automatic segmentation and implicit surface representation of dynamic cardiac data — The Visual Computer, 2024.

Andy Thai, I. Gradus-Pizlo, Z. Pizlo, H. Sahin, M. Gopi · DOI

Projects & Software

CNCM AAV Enhancer Gallery

Gallery of AAV enhancer sequences for targeted gene delivery.

URL

RegBoost

3D Laplacian interpolation framework using geometric feature priors for mouse brain image registration; complements any registration pipeline.

Repository · Paper

DVFOpt

Optimization procedure that adjusts any DVF to eliminate local folding artifacts with minimal deviation from the input field.

Repository (coming soon)

Implicit Heart

Implicit function representation for dynamic cardiac data; enables 3D/4D reconstruction and ejection fraction estimation.

Repository · Paper

Teaching

ICS 6N: Linear Algebra — TA/Reader/Instructor Support, multiple terms 2019-2024

UC Irvine · Winter/Spring/Summer/Fall terms across 2019-2024

ICS 32 / 32A / 33 / 45C — Teaching Assistant/Reader, 2018-2021

UC Irvine · Programming with Software Libraries, Intermediate Programming, C++ as a Second Language

COGS 189: Brain-Computing Interfaces — Instructional Assistant, 2018

UC San Diego

Talks

Automatic segmentation and implicit surface representation of dynamic cardiac data — CGI 2024, Geneva, Switzerland. (From journal work above.)
RUBI-PAL Robotics — Contextual Robotics Institute Forum (2017-2018), UCSD.

Service

Session Chair — CGI 2024.
Invited Panelist — UCSD ACSP Post-Grad Panel (2021-2024), Cal-Bridge Students Panel (2022), CSP Alumni Q&A (2021).
Leadership Coach — DECADE PLUS, UCI (2019-2021).
Various leadership & outreach roles — UCSD Chancellor's Scholars Program and Alliance (2014-2018).

Contact

Links

Email: [enable email]
Site: ics.uci.edu/~athai5
Links: Google Scholar · ORCID · GitHub · LinkedIn

Office

By appointment.
Falling Leaves Foundation Medical Innovation Building or Donald Bren Hall.